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Musculoskeletal manifestations of HIV infection

Department of Radiology, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, UK

• Musculoskeletal manifestations of HIV disease include aseptic inflammation, infection, neoplasia and therapy-related side effects.
  
• Lymphoma and pyomyositis are usually encountered when the CD4 count is markedly reduced.
  
• There is increased incidence of immune-mediated connective tissue disease in HIV infection.
  
• Infection may arise in the superficial soft tissues, muscles, joints and marrow cavity.
  
• Kaposi's sarcoma and non-Hodgkin's lymphoma are the commonest neoplastic conditions.
  
• Plain radiography, ultrasound, CT and MRI all have a role to play in patient assessment and management.
  

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